Research

Assisted by major technological breakthroughs, the past decades have witnessed transformative advances in genetics, structural biology, and biochemistry. Together, these fields have revealed the fundamental architecture of life. We are now at the cusp of integrating this knowledge to understand how the components of life dynamically interact and coordinate within multicellular organisms. These spatiotemporal interactions orchestrate the symphony of life and ultimately define its animate nature. 

The interdisciplinary research in our group integrates technology development, quantitative modeling, and biological discovery. By developing advanced bioimaging tools (including super-resolution microscopy, light-sheet microscopy, and adaptive optics), bioelectronics devices (such as nanoelectronics and flexible electronics), and computational approaches (including deep learning), we aim to Measure, Modulate, and Model subcellular dynamics within spatially heterogeneous and temporally evolving living systems. Through these efforts, we seek to address fundamental questions in cell and developmental biology, tissue–device interfaces, mechanobiology, and neuroscience.